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Welcome to Skin Lab!

The idea behind SkinLab is to offer skin treatments and skincare advice that give you real results.

I hope this blog will help you understand your skin better

I LOVE my job.

Im obsessed about skin care that is proven to work & I am passionate about delivering a facial service that gives visible results. 

The idea behind SkinLab is to offer skin treatments and skincare advice that give you real results.

Long lasting & improved skin conditions are achieved with clinical treatments but here at SkinLab each treatment is delivered traditional “hands on” style that includes lots of massage therapy, and this is the difference. 

This method ensures that you leave feeling your absolute best , inside and out. 

I love getting to know each of my clients, creating a relationship with each one of you makes my job such a joy.

ACNE, A new understanding.

We now have a clearer understanding of acne and its pathogenesis.

New research regarding 4 main causing factors allow us to precisely treat the skin more efficiently without causing sensitivity or harm to the surrounding healthy skin. 

We have 4 main factors that we need to understand and treat to ensure improvement in this skin condition:

• Micro comedone
• Biofilm formation
• Quorum sensing
• Drug resistance

MICROCOMEDONE

The comedone is a key layer in the formation of acne. It is considered the first element in the development of acne , representing a clinical non-visible precursor lesion of acne. They can be induced by sebaceous secretions , a buildup of dead cells within the sebaceous unit as well as altered follicular pathways. They may lead to more inflammatory acne such as pustules and papules. 

The micro comedones can rest “hidden”in the folic for up to 8 weeks before we see an acne lesion appear In cases that involved this , targeting the formation of microcomedones is essential in the prevention and control of acne, we will need at least 8 weeks to break the cycle of new comedones formation.

What creates the Micro comedones?

• Increased sebum exertion dn production
• Change in the quality of the oil secreted
• Altered exfoliation rate and efficiency 

Our skin creates its own mix of lipids and cholesterol and triglycerides to lubricate the skin, and retain water within the lower tissues. This mix is antimicrobial to prevent unabated pathogens affecting our skin , it is rich in antioxidants and also plays a part in sun protection. The sebum produced by patients suffering with acne has an altered ratio of these lipids, it has less linoleic acid, it loses its antioxidant profile and becomes the “free radical” provoking inflammation when the quantity is excessive. We will also see the proinflammatory oil activist neuropeptides ; TLR 1 that is located on the sebocyte cell, Thi invokes capillary dilation, further spending of inflammation involving the deep dermis layer of the skin. 

As with all acne there is a hormonal component to the issue, the Androgen influence is significant  alongside his testosterone resulting in 5 ADHT actuation. Testosterone is converted  enzymatically converts  5A DHT to the troublesome 5 alpha reductase- a major player in acne formation as it also alters the composition of the skin lipid profile  These hormones are seen in the skin as opposed to systemically, very often not showing up in systemic blood testing. 

BIOFILM FORMATION

We now have many studies to show a clear link between C.Acnes Bacteria and the biofilm that forms within the “community” of large numbers of this bacteria on the skin.

A biofilm is prevalent in chronic acne, menopause and stubborn to treat acne  to its resistance to treatment 

What is a biofilm? This is a “collection of microorganisms encased in a wall of substances secreted by collective organisms (sessile)”. The community of bacteria grows together via signally or by talking to each other (quorum sensing 0, they can behave platonically or in many cases behave pathogenetically. As a group they form a stick glue that adheres them to the skin and inside the pilosebaceous unit ( follicle) hoping to preserve acne bacteria and allow them to flourish. 

Unfortunately, biofilm formation in your skin means the usual methods of treatment will not work as efficiently or at all as the bio film becomes drug resistant ( resistant to antibiotic, benzoyl peroxide, retinoic acid). It will encourage the formation of micro comedones, triggering inflammation, induced proinflammatory cytokines and increases the pathogenicity of C. Acnes.

QUORUM SENSING

As mentioned  above Quorum sensing is bacterial-to-bacteria communication. This is  a key player in biofilm formation . The micro organisms create auto inducers that change gene expression, becoming more resistant and stronger. Their pathogenic behaviour becomes more regressive resulting in a community that “attacks” their healthy opponents.

Breaking this communication leads to breaking the biofilm. 

MEDER BEAUTY APPROACH TO ACNE TREATMENT.

 EU-SEB Concentrate has changed anti-acne skin care for the better.

This highly effective serum is formulated to treat acne, oily and inflamed skin. Microbiome-friendly concentrate quickly eliminates acne without the side effects of acids and retinol, eliminating red bumps, blemishes and blotches, prevents greasy shine, minimises pores and reduces blackheads.

This serum contains clinical dosage of 3 ingredients:

• Prebiotic
• Morinda, a plant stem cell extract
• Bioflavonoids

Prebiotic Bio E Coli, a pre biotic is used to inhibit harmful and unwanted baterías , helping to restore the balance to the microbiome, retire the barrier and to moisturise.

This is an excellent choice for menopausal acne, stubborn to treat and resistant to treat acne as it stimulates our natural anti microbial agent defensin- beta defensin in 3 days of use.

Stem cells from plant called Morinda Citifrolia are used as anti quorum sensing to block bacteria-to-bacteria communication signals, this will inhibit C.Acnes biofilm formation and is an anti-autoinducer helping to revert the pathogenic behaviour of bacteria to a more platonic or friendly state.

Morinda extract suppresses C.Acne growth and is also shown to revert the free radical behaviour of the sebum  normalised to its previous  antioxidant protective potential. 

A Bioflavonoid derived from a plant named Malclura Cochinchinensis, is clinically shown to reduce sebum production by 30% within days of use whilst also reducing the growth of C.Acnes.                       This flavonoid is also proven to reduce all enzyme activation related to antic behaviour in particular it downregulates or reduces the TLR 1 pro- inflammatory pathway, which will reduce redness and local inflammation quickly.

Malclura binds or closes off the retinoid receptors on the individual skin cell, therefore reducing the hormonal effect of 5 alpha reductase activity whilst also  diminishing sebum production. 

EQUADERM by Meder.

Microbiome-friendly Equa-Derm Cream is the best solution for oily, porous skin prone to inflammation. It restores healthy microflora, reduces the activity of harmful bacteria and inflammation, moisturises and evens out the complexion.

Avocutin extracted from avocado reduces sebum production (down 30% after 3 weeks of daily use) and eliminates greasy shine.

Both of these home care products are used alongside an initial 5 week course of Meder Beauty Eu-Seb facial treatments and 5 LED , light emitting diode therapy to help rapidly reduce your acne. 

These facial treatments will control acne, breakouts and oily skin.

Clinical strength Eu-Seb Concentrate reduces acne-causing bacteria by 92% in 24 hours.

In the clinic we use a probiotic enzyme exfoliation to encourage removal of follicular debris, extraction if needed , EU Seb Mask to reduce inflammation, redness and acne lesions and LED therapy to help start rejuvenation of the skin.

 If you are struggling with acne and you feel you need help you can contact me on 646083106. 

Together we can tackle this skin issue and help restore your skin back to health.